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Resumption Recommendation Expected

Officials in the US are expected to give the go-ahead to resume using Johnson & Johnson's SARS-CoV-2 vaccine, the Washington Post reports.

Officials from the Food and Drug Administration and Centers for Disease Control and Prevention recommended earlier this month that inoculations with J&J's vaccine be paused while they investigated reports of rare, but serious blood clots combined with low blood platelet levels.

According to the Post, officials are expected to recommend that a new warning statement about the possibility of the rare complication be added to fact sheets about the vaccine. It notes that that would be in line with what European regulators announced earlier this week. The European Medicines Agency said that though the vaccine may be associated with an increased risk of blood clots, its benefit of preventing COVID-19 outweighs the risk.

The Post adds that an official announcement is expected following the meeting Friday of a CDC advisory panel.

The Scan

Suicidal Ideation-Linked Loci Identified Using Million Veteran Program Data

Researchers in PLOS Genetics identify risk variants within and across ancestry groups with a genome-wide association study involving veterans with or without a history of suicidal ideation.

Algorithm Teases Out Genetic Ancestry in Individuals at Biobank Scale

Researchers develop an algorithm known as Rye to tease apart ancestry fractions in admixed individuals at a biobank-scale, applying it to 488,221 UK Biobank participants in Nucleic Acids Research.

Multi-Ancestry Analysis Highlights Comparable Common Variants at Complex Trait-Linked Loci

Researchers in Nature Genetics examine common variants implicated in more than three dozen conditions, estimating genetic effect similarities across ancestry tracts in admixed individuals.

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.