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The first trial using CRISPR within the human body is to begin this fall to treat a form of blindness, according to the Associated Press.

Editas Medicine and Allergan plan to enroll 18 people with Leber congenital amaurosis, a genetic form of blindness that affects the retina, in their study. According to the AP, Leber congenital amaurosis is the most common cause of inherited childhood blindness.

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Researchers uncovered the HIV virus within a tissue sample collected in 1966, the Atlantic reports.

The Washington Post writes that humans may have contributed to the extinction of cave bears some 20,000 years ago.

In PLOS this week: gene variant may protect against trypanosomiasis, GLIS3 role in type 2 diabetes, and more.

At a meeting this week, researchers and others discussed the regulatory oversight needed for germline genome editing.