Skip to main content
Premium Trial:

Request an Annual Quote

Prion Pause to Investigate

A three-month moratorium on prion research has been instituted at public research institutions in France after a retired lab worker was diagnosed with Creutzfeldt-Jakob disease, Science reports.

It adds that an investigation is underway to determine whether the individual, who worked at the National Research Institute for Agriculture, Food, and Environment, contracted Creutzfeldt-Jakob at work.

According to Science, a previous lab accident at INRAE led to the 2019 death of Émilie Jaumain. She died 10 years after pricking her thumb while working with prion-infected mice, it adds, noting that the link between her accident and death was largely clear as she had variant CJD, which has essentially disappeared from Europe. Her family has brought both criminal charges and an administrative suit against the lab, it says. Science adds that Jaumain's death led to the tightening of safety rules at prion labs.

It notes that more information is needed to determine whether the newly affected individual has vCJD or classic CJD, which it notes can occur sporadically.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.