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To Prevent That Churning Stomach

Canada is using whole-genome sequencing to track contaminated foods that have made people ill, the CBC reports. It adds that some four million Canadians become sick each year from eating contaminated food.

According to the CBC, scientists at the Canadian Food Inspection Agency have sequenced the genomes of foodborne pathogens like Salmonella, Listeria, and E. coli and use their sequences to identify what organism may have made a person sick by comparing them to samples from that patient.

"This helps food safety investigators do a much better job of identifying the food vehicles that are making people sick and also identifying sources of contamination in the food manufacturing environment," Burton Blais, from the Canadian Food Inspection Agency's Ottawa lab, tells the CBC.

The CBC adds that this approach coupled with other techniques enabled inspectors to trace a 2017 Salmonella outbreak to raw, breaded chicken products and to then implement new regulations to minimize Salmonella growth to prevent illness.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.