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Predicting the Course

Canadian researchers found that determining how different proteins interact in tumors can be used to predict a woman's chances at surviving breast cancer. As they report in Nature Biotechnology, scientists led by the University of Toronto's Jeffrey Wrana first scoured the literature for proteins that interact with many other proteins and then looked at genome-wide expression from 79 human tissues to identify in which tissues interacting proteins were co-expressed to identify hub proteins. They then applied that approach to studying breast cancer tissues from 350 women and saw that women who survived the disease had a different protein network organization than those who did not.

The Scan

Rise of BA.5

The New York Times reports that the Omicron subvariant BA.5 has become the dominant version of SARS-CoV-2 in the US.

UK Health Secretary Resigns

Sajid Javid, the UK health secretary, resigned along with Chancellor Rishi Sunak, saying they cannot work with Prime Minister Boris Johnson's government, CNN reports.

Clones From Freeze-Dried Cells

A team in Japan has cloned mice from freeze-dried skin cells, according to the Guardian.

Genome Research Papers on Craniosynostosis, Macaque Retrotransposition, More

In Genome Research this week: structural variants in craniosynostosis, LINE-1 activity in rhesus macaque brain, and more.