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Predicting the Course

Canadian researchers found that determining how different proteins interact in tumors can be used to predict a woman's chances at surviving breast cancer. As they report in Nature Biotechnology, scientists led by the University of Toronto's Jeffrey Wrana first scoured the literature for proteins that interact with many other proteins and then looked at genome-wide expression from 79 human tissues to identify in which tissues interacting proteins were co-expressed to identify hub proteins. They then applied that approach to studying breast cancer tissues from 350 women and saw that women who survived the disease had a different protein network organization than those who did not.

The Scan

Gone, But Now Reconstructed SARS-CoV-2 Genomes

In a preprint, a researcher describes his recovery of viral sequences that had been removed from a common database.

Rare Heart Inflammation Warning

The Food and Drug Administration is adding a warning about links between a rare inflammatory heart condition and two SARS-CoV-2 vaccines, Reuters reports.

Sandwich Sampling

The New York Times sent tuna sandwiches for PCR analysis.

Nature Papers Describe Gut Viruses, New Format for Storing Quantitative Genomic Data, More

In Nature this week: catalog of DNA viruses of the human gut microbiome, new dense depth data dump format to store quantitative genomic data, and more.