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Researchers at Columbia University and the University of Pennsylvania describe an apparent role for the chromosome 15 gene C2CD4A in insulin secretion from pancreatic beta-cells and related susceptibility to type 2 diabetes (T2D). Starting with a locus associated with T2D in prior genome-wide association studies, the team searched for overlapping super-enhancers of FoxO1, which has been implicated in beta-cell dysfunction.

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Nature News reports that recent proposed changes to the US National Science Foundation have raised concerns about a shift away from the agency's focus on basic research.

Noel Rose, the "father of autoimmunity," has died at 92, the Washington Post reports.

According to CNN, Legionella was discovered in buildings leased by the Centers for Disease Control and Prevention as they reopened following coronavirus pandemic-related closures.

In PLOS this week: genetic analysis of malaria parasite populations in Southeast Asia, genomic surveillance of yellow fever virus in São Paulo, and more.