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Researchers at Columbia University and the University of Pennsylvania describe an apparent role for the chromosome 15 gene C2CD4A in insulin secretion from pancreatic beta-cells and related susceptibility to type 2 diabetes (T2D). Starting with a locus associated with T2D in prior genome-wide association studies, the team searched for overlapping super-enhancers of FoxO1, which has been implicated in beta-cell dysfunction.

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The US Department of Justice has proposed a rule change to enable DNA to be collected from migrants, the Associated Press reports.

Bernard Fisher, a surgeon who changed how breast cancer is treated, has died at 101, the New York Times reports.

Washington Post columnist writes that she is skeptical about DNA-based diets.

In PNAS this week: recurrent inactivation of DEPDC5 in gastrointestinal stromal tumors, taxonomic reliability of GenBank sequences, and more.