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Researchers from the University of Massachusetts and the University of Copenhagen describe four human adipocyte fat cell subtypes, along with the corresponding mesenchymal progenitor cells giving rise to them. Using RNA sequencing, the team profiled gene expression patterns in mesenchymal progenitor cells generated at different stages of differentiation in the lab, uncovering four specialized adipocyte subtypes that showed distinct tissue functions in follow-up experiments.

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Bloomberg reports that vaccine developers won't have to conduct large trials of updated vaccines or vaccine boosters aimed at new viral variants.

The SARS-CoV-2 variant uncovered in California may be more transmissible and partially evade vaccine-induced antibody response, the Los Angeles Times reports.

Francis deSouza, the CEO of Illumina, calls for a global SARS-CoV-2 genomics surveillance network, according to the Financial Times.

In PNAS this week: immunotherapy for hard-to-treat breast cancers, effects of oncogenic histone H3K36M mutations, and more.