Close Menu

A Duke University-led team characterizes an autism spectrum disorder-associated, alternatively spliced version of the ANK2 gene, which produces a so-called giant ankyrin-B (ankB). Using CRISPR-Cas9 gene editing, the researchers produced mice with ASD-related splice changes affecting exon 37 of ANK2 before tracking mouse behavior and brain connectivity — analyses that highlighted enhanced neuronal axon branching and other brain connection changes in the giant ankB mice.

To read the full story....

...and receive Daily News bulletins.

Already have a GenomeWeb or 360Dx account?
Login Now.

Don't have a GenomeWeb or 360Dx account?
Register for Free.

The University of California, Berkeley's Jennifer Doudna reflects at Science on the anniversary of the announcement of the birth of twin girls who underwent genome editing.

By studying its enamel proteome, researchers have found the ancient ape Gigantopithecus blacki belongs to a sister clade to that of orangutans.

Bloomberg Businessweek discusses genomics with BGI's Wang Jian.

In Science this week: researchers find transplanting the gut microbiome in mice affects physiology, and more.