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Researchers from the US and Lebanon profile somatic mutation patterns in dozens of glioblastoma (GBM) tumors from Lebanese patients in a study appearing in PLOS One. Using exome sequencing, the team assessed 60 patient-derived GBM tumor samples from 37 men and 23 women with the aggressive brain tumor type, looking in particular at mutational signatures and somatic variant patterns across 50 genes associated with GBM in other populations.

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Moderna reports its vaccine is effective against new SARS-CoV-2 strains, though it is also developing a booster, according to the New York Times.

A new analysis suggests the B.1.1.7 strain of SARS-CoV-2 could be deadlier than previous ones, according to the Guardian.

NPR reports Merck is halting the development of its two candidate SARS-CoV-2 vaccines following disappointing Phase 1 results.

In PLOS this week: gene mutation linked to inherited venous thrombosis, lncRNA patterns in the Asian tiger mosquito, and more.