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A University College London Institute of Ophthalmology-led team describes SPATA13/ASEF2 gene mutations that appear to contribute to a form of glaucoma for a paper in PLOS Genetics. The researchers relied on genome sequencing, in combination with genetic linkage analyses, to search for genetic culprits behind primary angle-closure glaucoma (PACG) in members of an affected multi-generation Caucasian family.

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