The Pair of Them

Matched tumor-normal pairs are necessary to reliably identify and interpret mutations found in patients' tumors to guide treatment, according to researchers from Johns Hopkins University School of Medicine and Personal Genome Diagnostics.

However, as Julia Karow writes at GenomeWeb, many diagnostic labs only sequence tumor tissue and not matched normal tissue, often for reasons of cost.

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The Seattle Times writes that pharmacogenomics testing can help choose medications that may work best for people with depression.

Researchers report that deleting one gene from butterflies affects their wing coloration patterns, according to the Washington Post.

In PNAS this week: genome sequencing of weevil symbionts, retinoid X receptor deletion in lung cancer metastasis, and more.

Sequencing could help combat foodborne illnesses, according to a blog post by Food and Drug Administration officials.