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When she began working on CRISPR, the University of California, Berkeley's Jennifer Doudna remembers thinking "this is probably the most obscure thing I ever worked on," as she tells the New York Times.

Now because of that obscure work, Doudna and her colleague Emmanuelle Charpentier at Umea University are now embroiled in a patent dispute and an ethical debate.

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Nature News writes that viral genomic surveillance in the US faces systemic issues.

President Joe Biden is seeking an increase in federal spending, including higher budgets for the National Institutes of Health and Centers for Disease Control and Prevention.

A small, early-stage trial of a combination therapy for brain cancer reports favorable responses in two patients, according to the Guardian.

In PLOS this week: sex-stratified genome-wide association study of chronic pain, sequencing data from Indigenous Mexican groups, and more.