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OA 'Muscle'

Two major private biomedical research funders have joined Plan S, the recently launched European open-access initiative, ScienceInsider reports.

Science Europe, a coalition of European funding agencies, developed Plan S, which centers on 10 key principles, especially requiring publicly funded researchers to publish their results in open-access journals. Eleven countries including the UK, France, and the Netherlands signed on to the program, which was announced in September.

Now, ScienceInsider reports that the Wellcome Trust and the Bill & Melinda Gates Foundation, which fund $1.3 billion and $1.2 billion in research each year, respective, have joined the initiative. This, it says, will "add a lot of funding muscle" to the program.

The two charities had previously championed open-access publishing, though allowed their grantees to publish in hybrid open-access journals, in which free and subscription articles appear side by side, but will no longer allow that. Wellcome tells ScienceInsider it had tolerated that approach as part of a transition to open access, but says that transition is over.

The Scan

Nucleotide Base Detected on Near-Earth Asteroid

Among other intriguing compounds, researchers find the nucleotide uracil, a component of RNA sequences, in samples collected from the near-Earth asteroid Ryugu, as they report in Nature Communications.

Clinical Trial Participants, Investigators Point to Importance of Clinical Trial Results Reporting in Canadian Study

Public reporting on clinical trial results is crucial, according to interviews with clinical trial participants, investigators, and organizers from three provinces appearing in BMJ Open.

Old Order Amish Analysis Highlights Autozygosity, Potential Ties to Blood Measures

Researchers in BMC Genomics see larger and more frequent runs-of-homozygosity in Old Order Amish participants, though only regional autozygosity coincided with two blood-based measures.

Suicidal Ideation-Linked Loci Identified Using Million Veteran Program Data

Researchers in PLOS Genetics identify risk variants within and across ancestry groups with a genome-wide association study involving veterans with or without a history of suicidal ideation.