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The Next Batch

With a number of SARS-CoV-2 vaccines available, some researchers are turning to developing vaccines that are easier to store or administer, NPR reports.

It notes that while the three authorized vaccines in the US are effective, they are not necessarily 'ideal' vaccines. An 'ideal' vaccine, the University of Washington's Deborah Fuller tells it, would be "administered in a single shot, be room temperature stable, work in all demographics and, even pushed beyond that, ideally be self-administered."

According to NPR, researchers at Vaxart are working on a SARS-CoV-2 vaccine that could be taken as a pill, while researchers at University of Alabama at Birmingham are working with the others at Altimmune to develop one that is delivered as a nasal spray. At the same time, other researchers are working on vaccines that better mimic the spike protein of SARS-CoV-2 or how the spike protein is presented in the vaccine.

Nicole Lurie, a strategic adviser at the Coalition for Epidemic Preparedness Innovation, tells it that while developing SARS-CoV-2 vaccines within a year was a triumph, developers now have to be nimble and move quickly.

The Scan

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.

Adenine Base Editor Targets SCID Mutation in New Study

Researchers from the University of California, Los Angeles, report in Cell that adenine base editing was able to produce functional T lymphocytes in a model of severe combined immune deficiency.

Researchers Find Gene Affecting Alkaline Sensitivity in Plants

Researchers from the Chinese Academy of Science have found a locus affecting alkaline-salinity sensitivity, which could aid in efforts to improve crop productivity, as they report in Science.

International Team Proposes Checklist for Returning Genomic Research Results

Researchers in the European Journal of Human Genetics present a checklist to guide the return of genomic research results to study participants.