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A new and efficient CRISPR system for genome editing in plants is reported in Nature Plants this week. In the study, a University of Maryland-led team focused on the nuclease Cas12b from various bacteria — Alicyclobacillus acidoterrestris, Alicyclobacillus acidiphilus (Aa), Bacillus thermoamylovorans, and Bacillus hisashi — for genome editing in rice, finding that AaCas12b was the most efficient of the four for targeted mutagenesis.

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