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A method for improved single-cell RNA sequencing (scRNA-seq) data preprocessing is presented in Nature Biotechnology this week. Preprocessing — the quantification of transcript or gene abundances in individual cells from a scRNA-seq experiment — is hampered by challenges such as the memory requirements for handling increasingly large volumes of data.

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A small, early-stage trial of a combination therapy for brain cancer reports favorable responses in two patients, according to the Guardian.

Nature News writes that viral genomic surveillance in the US faces systemic issues.

President Joe Biden is seeking an increase in federal spending, including higher budgets for the National Institutes of Health and Centers for Disease Control and Prevention.

In PLOS this week: sex-stratified genome-wide association study of chronic pain, sequencing data from Indigenous Mexican groups, and more.