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A team led by scientists from Aalborg University reports a new method for high-throughput amplicon sequencing in Nature Methods this week. The approach combines unique molecular identifiers with sequencing of long amplicons on either Oxford Nanopore Technologies (ONT) or Pacific Biosciences platforms. According to its developers, the workflow generates higher single-molecule accuracy and lower chimera rates with amplicons than was previously possible on long-read sequencing platforms.

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