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A computational method for predicting genome folding using only DNA sequence as an input is reported in Nature Methods this week. The convolutional neural network, dubbed Akita, takes in approximately one megabase of DNA sequence and predicts contact frequency maps for all pairs of around 2-kb bins within this region, according to the method's developers at the Gladstone Institute of Data Science and Biotechnology and Calico Life Sciences.

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The UK and the European Union have come to a sticking point in the negotiation of how the UK might remain involved in the Horizon Europe research program, the Guardian reports.

The New York Times reports that experts pushed during a meeting of an FDA advisory board for the agency to require more safety data from SARS-CoV-2 vaccine trials.

The Washington Post reports Moderna expects that it will have enough data on its candidate SARS-CoV-2 vaccine to submit to regulatory authorities by mid-November.

In Science this week: ANXA11 variants affect calcium homeostasis and stress granule disassembly in ALS, and more.