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A description of the genomic alterations associated with the loss of nearly every single non-essential gene contained in the yeast Saccharomyces cerevisiae gene-knockout collection (YKOC) is presented in Nature this week. To build the resource, researchers sequenced the whole genomes of nearly all of the 4,732 strains comprising the homozygous diploid YKOC, extracting information on copy-number variation of tandem and interspersed repetitive DNA elements.

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The Los Angeles Times reports that a case of the novel coronavirus making people ill in China has been reported in the US. 

A bipartisan group of senators has introduced a bill seeking increased funding for certain fields, including synthetic biology, ScienceInsider reports. 

Discover magazine writes that paleoproteomics is increasing being used in archaeology, paleoanthropology, and paleontology, including a recent study of a 6,000-year-old ring. 

In Nucleic Acids Research this week: mutagenic effects of ultraviolet "A" light, post-transcription effects of synonymous mutations, and more.