Skip to main content
Premium Trial:

Request an Annual Quote

mRNA-Based Vaccine on the Way in China

China may be on the cusp of approving its first mRNA-based vaccine against SARS-CoV-2, Nature News reports.

It notes that seven vaccines have already been approved in China. The two main ones in use, from Sinovac and Sinopharm, rely on inactivated viruses and are not as effective as the mRNA vaccines from Pfizer–BioNTech and Moderna, it adds.

According to Nature News, a small clinical trial of the ArCoV vaccine candidate developed by Abogen Biosciences, has indicated that when it is given to previously vaccinated adults as a booster shot, it leads to a stronger immune reaction than the inactivated virus-based vaccines. In a preprint, the investigators said their findings support its use as a booster.

Feng Gao from Jinan University in Guangzhou, China, tells it that whether the vaccine "will receive official approval will depend on its phase III trial result. Not every mRNA-vaccine candidate will succeed."

Nature News adds that a handful of other Chinese-developed mRNA-based vaccines are also in trials.

Filed under

The Scan

Open Pediatric Brain Tumor Atlas Team Introduces Genomic Data Collection, Analytical Tools

A study in Cell Genomics outlines open-source methods being used to analyze and translate whole-genome, exome, and RNA sequence data from the Pediatric Brain Tumor Atlas.

Neurological Outcomes Linked to Innate Immune Features After Cardiac Arrest

Researchers reporting in Med dig into immune features found a few hours after cardiac arrest that correspond with neurological outcomes.

Mouse Study Finds Circadian Rhythm-Related Gene Expression Changes Linked to Sleep Apnea

A paper in PLOS Biology reveals tissue-specific circadian rhythm and gene expression patterns in an intermittent hypoxia-based mouse model of obstructive sleep apnea.

Polygenic Risk Score to Predict Preeclampsia, Gestational Hypertension in Pregnant Women

Researchers in Nature Medicine provide new mechanistic insights into the development of hypertensive disorders of pregnancy, which may help develop therapeutics.