Skip to main content
Premium Trial:

Request an Annual Quote

For Long Life: Genetic Testing

A relatively inexpensive saliva test could tell someone their expected lifespan based on their genes, the Telegraph reports.

It adds that researchers from the University of Edinburgh conducted a genome-wide association study that drew on the genetic information from more than half a million people who were asked how long their parents lived. As Edinburgh's Peter Joshi and colleagues report in eLife, they validated six loci previously linked to lifespan and uncovered 11 novel ones. The lead SNPs are linked to autoimmune, cardiometabolic, neuropsychiatric, or smoking-related disease, the researchers note. All together, they add that these lifespan-linked variants explain a difference of about five years across the deciles.

"If we take 100 people at birth, or later, and use our lifespan score to divide them into ten groups, the top group will live five years longer than the bottom on average," Joshi tells the Telegraph. It adds that a test using these findings could be folding into current tests, which cost about £150 ($193).

The Scan

RNA Editing in Octopuses Seems to Help Acclimation to Shifts in Water Temperature

A paper in Cell reports that octopuses use RNA editing to help them adjust to different water temperatures.

Topical Compound to Block EGFR Inhibitors May Ease Skin Toxicities, Study Finds

A topical treatment described in Science Translational Medicine may limit skin toxicities seen with EGFR inhibitor therapy.

Dozen Genetic Loci Linked to Preeclampsia Risk in New GWAS

An analysis of genome-wide association study data in JAMA Cardiology finds genetic loci linked to preeclampsia that have ties to blood pressure.

Cancer Survival Linked to Mutational Burden in Pan-Cancer Analysis

A pan-cancer paper appearing in JCO Precision Oncology suggests tumor mutation patterns provide clues for predicting cancer survival that are independent of other prognostic factors.