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Genome-Wide Association Study Data Resource GWAS Central Updated

An update to GWAS Central, a web-based collection of summary-level genome-wide association study data and analysis tools, is reported in Nucleic Acids Research this week. According to its developers at the University of Leicester, the resource now contains over 72.5 million P-values for more than 5,000 studies testing over 7.4 million unique genetic markers investigating more than 1,700 unique phenotypes. GWAS Central has also been integrated with mouse disease model data to support insights into the functional impact of human genetic variation and been expanded to include mouse gene-phenotype associations observed during mouse gene knockout screens. Additional updates include the mapping of terms from mammalian and human phenotype ontologies and new interactive interfaces to find, correlate, and view human and mouse genotype-phenotype associations

The Scan

ChatGPT Does As Well As Humans Answering Genetics Questions, Study Finds

Researchers in the European Journal of Human Genetics had ChatGPT answer genetics-related questions, finding it was about 68 percent accurate, but sometimes gave different answers to the same question.

Sequencing Analysis Examines Gene Regulatory Networks of Honeybee Soldier, Forager Brains

Researchers in Nature Ecology & Evolution find gene regulatory network differences between soldiers and foragers, suggesting bees can take on either role.

Analysis of Ashkenazi Jewish Cohort Uncovers New Genetic Loci Linked to Alzheimer's Disease

The study in Alzheimer's & Dementia highlighted known genes, but also novel ones with biological ties to Alzheimer's disease.

Tara Pacific Expedition Project Team Finds High Diversity Within Coral Reef Microbiome

In papers appearing in Nature Communications and elsewhere, the team reports on findings from the two-year excursion examining coral reefs.