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An international team led by investigators at the University of Exeter outline apparent links between altered biological aging and mutations affecting epigenetic regulators, particularly DNA methyltransferase or histone methyltransferase enzymes. The researchers did array-based methylation profiling in related and unrelated individuals with Tatton-Brown-Rahman syndrome, who carried known alterations in the DNA methyltransferase-coding gene DNMT3A.

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Stephen Hahn, the nominee to lead the US Food and Drug Administration, underwent a Senate confirmation hearing yesterday, the Washington Post reports.

The US Food and Drug Administration has approved an RNA interference drug to treat acute hepatic porphyria.

Gizmodo looks over the past decade of consumer DNA testing to find the field to be lacking.

In Nature this week: native RNA sequencing and analysis of a human poly(A) transcriptome, nanopore sequencing-based method to analyze short tandem repeat expansions, and more.