Researchers at the University of Pavia, Yale University, and elsewhere present an improved reference genome for the Asian tiger mosquito Aedes albopictus, an invasive species known for transmitting arboviruses such as dengue, Zika, and chikungunya virus. Using PacBio long-read sequencing, combined with 10x Genomics and Hi-C proximity ligation scaffolding, bioinformatics, and other methods, the team put together a 2.5 billion-base Ae.