A gene called PIEZO2 may help people determine when they need to seek a bathroom, according to a new study.

A Scripps Research Institute-led team sent questionnaires to a dozen individuals deficient in PIEZO2 that asked not only how often they generally need to urinate each day, but also about any accidents or other urination-linked issues. They had homed in on PIEZO2, which encodes proteins that are activated when stretched or squeezed, in a previous study.