Finding Mutations that Protect

Feb 04, 2009

Technology Review has a Q&A with Ken Offit, chief of the clinical genetics service at Memorial Sloan-Kettering Cancer Center, who is leading a new study looking for protective variants in women with mutations in BRCA2. He hopes to use SNP arrays and a large number of study participants worldwide to find what factors might protect women who are genetically predisposed to getting breast cancer from getting it.

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The Scan

Harder to Breathe

Researchers tie a variant in ADAMTS3 to breathing difficulties in dissimilar dog breeds, according to Discover's D-brief blog.

Sequence From the Jomon Period

The Japan Times reports that researchers sequenced the genome of a woman who lived during the Jomon period.

Shifting Sands of Gene Variant Interpretation

Parents of children with rare genetic disease have to contend with shifts in the interpretation of genetic variants, the Wall Street Journal reports.

This Week in Science

In Science this week: single-nucleus RNA sequencing of brain tissue from individuals with autism, and more.

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