Sequencing the human genome has begun to transform medicine, Francis Collins, the director of the US National Institutes of Health, tells David Rubenstein at Bloomberg.

Collins notes that when the human genome was first sequenced that there was a lot of chatter that medicine would change almost instantly. But he tells Rubenstein that with the genome's complexity, to took a bit more time.

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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.