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Malignant cells in glioblastoma largely fall into four main cellular states, according to a new study appearing in Cell. A Harvard Medical School-led team conducted single-cell RNA-sequencing of 20 adult and eight pediatric glioblastoma cases for a total 24,131 cells, single-cell RNA-sequencing and lineage tracing of glioblastoma models, and bulk analysis of 401 samples from The Cancer Genome Atlas to pull together an integrative model of glioblastoma.

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Stephen Hahn, the nominee to lead the US Food and Drug Administration, underwent a Senate confirmation hearing yesterday, the Washington Post reports.

The US Food and Drug Administration has approved an RNA interference drug to treat acute hepatic porphyria.

Gizmodo looks over the past decade of consumer DNA testing to find the field to be lacking.

In Nature this week: native RNA sequencing and analysis of a human poly(A) transcriptome, nanopore sequencing-based method to analyze short tandem repeat expansions, and more.