While fourth- and eighth-graders in the US have performed better in the sciences on a national assessment than in the past, only about a third had a strong showing, the Associated Press reports. Further, only one in five high-school seniors obtained a 'proficient' or higher score, it adds.

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The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.