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Appeal Denied

The US Supreme Court on Monday denied a request by Ono Pharmaceutical to review a federal appeals court decision that added two scientists as inventors on company patents covering a new cancer treatment technology, Reuters reports. The technology involves using T cell-targeting antibodies to stimulate immune responses against cancer cells and was developed primarily by Tasuku Honjo, who won a Nobel Prize in 2018 for his work. The Dana-Farber Cancer Institute sued Ono, along with patent licensee Bristol-Myers Squibb, in 2015 seeking to have its researcher Gordon Freeman and former Genetics Institute scientist Clive Wood, both of whom collaborated with Honjo, added to patents covering the technology. According to Reuters, a US District Court found in 2019 that both scientists had made significant enough contributions to Ono-controlled patents that they should be listed as coinventors — a decision upheld by a US Circuit Court the next year. Ono asked the Supreme Court to review the rule, but the court declined, Reuters reports.

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The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.