Skip to main content
Premium Trial:

Request an Annual Quote

Antibiotic Usage Linked to Antibiotic Resistance Genes in Human Gut Microbiome

Widespread usage of antibiotics is linked to higher levels of antibiotic resistance genes (ARGs) in the human gut microbiome, according to a study appearing in Nature Communications this week. The use of antimicrobials has been shown to drive the evolution of resistance in pathogenic microbes, but the impact on the microbiome is poorly understood. In the new study, a team led by scientists from Chung-Ang University in Korea and the UK's Earlham Institute surveyed ARGs in 8,972 metagenomes, including more than 3,000 gut microbiomes from healthy people not taking antibiotics. They uncover highly significant correlations between both the total ARG abundance and diversity and per capita antibiotic usage rates across 10 countries spanning three continents and show that these correlations are principally driven by mobile resistance genes embedded in a central network component dominated by commensal organisms. The researchers also discover that individual human gut ARG profiles cluster into two types, including one that is associated with certain classes of resistance.

The Scan

ChatGPT Does As Well As Humans Answering Genetics Questions, Study Finds

Researchers in the European Journal of Human Genetics had ChatGPT answer genetics-related questions, finding it was about 68 percent accurate, but sometimes gave different answers to the same question.

Sequencing Analysis Examines Gene Regulatory Networks of Honeybee Soldier, Forager Brains

Researchers in Nature Ecology & Evolution find gene regulatory network differences between soldiers and foragers, suggesting bees can take on either role.

Analysis of Ashkenazi Jewish Cohort Uncovers New Genetic Loci Linked to Alzheimer's Disease

The study in Alzheimer's & Dementia highlighted known genes, but also novel ones with biological ties to Alzheimer's disease.

Tara Pacific Expedition Project Team Finds High Diversity Within Coral Reef Microbiome

In papers appearing in Nature Communications and elsewhere, the team reports on findings from the two-year excursion examining coral reefs.