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Another Dimension

In Futurism, Kristin Houser outlines an approach for mapping the 3D structure of the human genome.

Using "tyramide signal amplification sequencing," or TSA-Seq, she explains, a University of Illinois at Urbana-Champaign-led team mapped chromosomal distances from nuclear structures known as "nuclear speckles" in leukemia cells — work they reported in the Journal of Cell Biology yesterday.

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The Hastings Center's Erik Parens argues in a Scientific American opinion piece that the current pandemic underscores the need to reconsider the hope placed in genomic medicine. 

The Los Angeles Times writes that Operation Warp Speed has an ambitious timeline for developing a COVID-19 vaccine.

The Sydney Morning Herald reports that Australia is launching its trial of preconception carrier testing Tuesday.

In PNAS this week: autosomal genes commonly affected by loss-of-function variants, variants implicated in testis development disorders, and more.