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All the World's Genomes

The Smithsonian Institution is opening a virtual biodiversity genomics institute, ScienceInsider reports.

With is Smithsonian Institute for Biodiversity Genomics, the institution hopes to foster efforts to collect and catalog DNA from all life on Earth.

"Our goal is to pioneer novel genomic approaches, integrate them into biological endeavors throughout the Smithsonian, and serve as a resource for genomics research around the world," Pierre Comizzoli, the director of the Grand Challenges Consortia for Science at the Smithsonian, says in a statement.

ScienceInsider's Elizabeth Pennisi notes that the Smithsonian already allocates some $10 million a year for genomic research, but as part of this effort to coordinate biodiversity genomics globally, John Kress, the Smithsonian's interim under secretary for science, says he wants to raise $100 million over the next 10 years.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.