It's a balancing act, to be sure, to get and keep a core lab facility up-to-date with new technologies and services. There are many facets of running a shared resource that need to be considered when a core looks into acquiring or upgrading a tool or changing a service. There's the gamble of whether that new technology will be the one to take off or not — after all, no one wants to invest time and money in someone's Betamax and miss out on VHS.

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In PNAS this week: rare variants linked to bleeding disorder, comparison of whole-exome and whole-genome sequencing, and more.

George Church tells The Sunday Times that his group has inserted some woolly mammoth genes into elephant cells.

A Scientific Reports editor resigns over a new policy at the journal allowing researchers to pay to fast track the peer review of their manuscripts, and poll.

The National Cancer Institute's Harold Varmus discusses the state of cancer research with the New York Times.