Skip to main content

USPTO Publishes Two RNAi-Related Patent Applications: Nov 13, 2008

Premium
Title: RNA Interference Suppression of Neurodegenerative Diseases and Methods of Use Thereof
 
Number: 20080274989
 
Filed: June 2, 2005 PCT Filed: June 2, 2005
 
Lead Inventor: Beverly Davidson, University of Iowa
 
The invention, the patent application’s abstract states, “is directed to small interfering RNA molecules targeted against nucleic acid sequence that encodes huntingtin or ataxin-1, and methods of using these siRNA molecules.”
 

 
Title: RNAi Probes Targeting Cancer-Related Proteins
 
Number: 20080274996
 
Filed: May 6, 2008
 
Lead Inventor: Martin Gleave, University of British Columbia (Oncogenex)
 
The patent application, its abstract states, claims “RNAi sequences that are useful as therapeutics in the treatment of cancers of various types, including prostate cancer, sarcomas such as osteosarcoma, renal cell carcinoma, breast cancer, bladder cancer, lung cancer, colon cancer, ovarian cancer, anaplastic large cell lymphoma, and melanoma,” as well as Alzheimer's disease.
 
“These sequences target clusterin, IGFBP-5, IGFBP-2, both IGFBP-2 and -5 simultaneously, Mitf, and B-raf,” the abstract adds. “The invention further provides for the use of these RNAi sequences in the treatment of cancers of various types … and Alzheimer's disease, and a method of treating such conditions through the administration of the RNA molecules with RNAi activity to an individual.”

The Scan

Rise of B.1.617.2 in the UK

According to the Guardian, UK officials expect the B.1.617.2 variant to soon be the dominant version of SARS-CoV-2 there.

Anne Schuchat to Retire

Anne Schuchat is retiring after more than 30 years at the US Centers for Disease Control and Prevention, Politico reports.

US to Share More Vaccines

CNN reports that the US will share 20 million doses of the Moderna, Pfizer, and Johnson & Johnson SARS-CoV-2 vaccines with other countries.

PNAS Papers on Gene Therapy Platform, Aspergillus Metabolome, Undernutrition Model Microbiome

In PNAS this week: approach to deliver protein-based treatments to cells, pan-secondary metabolome of Aspergillus, and more.