Title: Therapeutic RNAi Agents for Treating Psoriasis
Filed: Oct. 21, 2005
Lead Inventor: Ken Reed, Benitec
According to the patent application's abstract, the invention "provides compositions and methods suitable for delivering RNAi agents against genetic targets in skin tissues so as to treat psoriasis."
Title: Therapeutic RNAi Agents for Treating Restenosis
Filed: Oct. 14, 2005
Lead Inventor: Linda Couto, Benitec
According to the patent application's abstract, the invention "provides compositions and methods suitable for delivering RNAi agents against genetic targets in vascular and adjacent tissue in vivo so as to treat restenosis."
Title: Apparatus and System Having Dry Gene-Silencing Compositions
Filed: Nov. 18, 2005
Lead Inventor: Barbara Robertson, Dharmacon
The patent application, its abstract states, covers "a reverse-transfection apparatus … for introducing siRNA into a cell to effect gene silencing. Such an apparatus can include a well plate having a well configured for transfecting cells. The well can include a substantially dry gene-silencing composition that has at least a first siRNA which silences a first target gene. The gene-silencing composition can be configured such that the at least first siRNA is capable of being solubilized or suspended in an aqueous medium in an amount sufficient for transfecting cells in the well. Additionally, the at least first siRNA can include a modification or a conjugate. The reverse-transfection apparatus can be provided as a kit or system that additionally includes cells, polynucleotide carriers, reverse transfection reagents, and the like."