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USPTO Publishes One RNAi-Related Patent

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Title: Nanoparticle Delivery Vehicle
 
Number: 7,332,586
 
Filed: July 10, 2002
 
Lead Inventor: Stefan Franzen, North Carolina State University
 
The patent, its abstract states, claims “a nanoparticle delivery vehicle comprising a nanoparticle, an active agent, and a nuclear localization signal and methods of modulating gene expression and protein expression employing the nanoparticle delivery vehicle.”
 
This nanoparticle, the abstract adds, has “a diameter of about 30 nm or less” and contacts “a target cell … whereby an active agent is delivered to the nucleus of a target cell. Another representative method includes … a nanoparticle having a diameter greater than or equal to about 30 nm, an active agent, and a nuclear localization signal, [which contact] a target cell with the nanoparticle delivery vehicle, whereby an active agent is delivered to the cytoplasm of a cell.”

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