This article has been updated to clarify Alnylam's partnership with Medtronic and statements regarding its liver cancer program.

By Doug Macron

When Alnylam Pharmaceuticals announced last week its latest product-development strategy, it said it reflected a shift of its focus onto "genetically defined diseases" offering the potential for "early commercialization opportunities."

It also marked the latest in a series of pipeline changeups the company has undertaken since it was founded in 2002.

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Technology Review reports that researchers in the US have used CRISPR to modify a number of human embryos.

Plant researchers plan to sequence some 10,000 samples that represent the major plant clades, ScienceInsider reports.

By introducing genes from butterfly peas and Canterbury bells, researchers in Japan have developed a blue chrysanthemum, according to NPR.

In Nature this week: a Danish reference genome, and more.