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Undisclosed Pharma to Evaluate Silence siRNA-Delivery Technology

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Silence Therapeutics this week announced that it has signed a deal under which one of its proprietary siRNA delivery technologies will be evaluated by an undisclosed “global pharmaceutical” company.

Specifically, Silence will formulate siRNAs provided by the pharmaceutical firm with its its drug-assembling cholesterol complex, or DACC, technology for intravenous delivery into the pulmonary vascular endothelium.

Both companies will undertake in vitro and in vivo studies of the siRNAs and select lead candidates for further development. Additional terms of the arrangement were not disclosed.

The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.