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Two RNAi-Related Patent Applications Published by the US Patent Office: May 6, 2005


Title: Nucleic Acid Nematicides.

Number: 20050091713.

Filed: Dec. 29, 2004.

PCT Filed: Dec. 17, 2002.

Inventor: Howard Atkinson, University of Leeds.

"The invention is the identification of double-stranded RNA nematicides to nematode genes and a screening assay for the identification of agents, typically dsRNA's, with nematicidal activity," the patent application's abstract states.

Title: Methods of Inhibiting Inflammation.

Number: 20050090426.

Filed: March 24, 2004.

Inventor: Richard Blumberg, Harvard Medical School.

"The invention provides a method of inhibiting inflammation in a mammal, by administering to the mammal composition containing a compound which inhibits the expression or activity of a microsomal triglyceride transfer protein," the patent application's abstract states.

The application specifically claims the inhibition of inflammation by administering to an inflamed tissue an siRNA inhibiting microsomal triglyceride transfer protein.


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