NEW YORK (GenomeWeb) — Through a combination of next-generation sequencing and CRISPR-Cas9-mediated genome editing, two sets of researchers homed in on the mechanisms of action for a handful of drugs and uncovered mutations that can lead to resistance to those drugs, as they reported in separate studies in Nature Chemical Biology yesterday.

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In Nature this week: omic analysis of permafrost microbes, hookworm genome, and more.

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