NEW YORK (GenomeWeb) — Through a combination of next-generation sequencing and CRISPR-Cas9-mediated genome editing, two sets of researchers homed in on the mechanisms of action for a handful of drugs and uncovered mutations that can lead to resistance to those drugs, as they reported in separate studies in Nature Chemical Biology yesterday.

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In Nature this week: mouse genome functional analysis, more sensitive chromatin immunoprecipitation, and more.

The Center for Data Innovation and HealthITNow argue for re-building of genomic research infrastructure.

A Senate committee has unanimously approved a bill to require articles resulting from federally funded projects to be made publicly available, according to ScienceInsider.

The US is heading toward another budget showdown, Nature News says.