In an effort to improve the screening and selection of lipid nanoparticle delivery vehicles for siRNA therapeutics, researchers from Merck have developed an in vitro assay designed to test how the particles will behave in vivo.

After systemic administration, lipid nanoparticles are exposed to a variety of biological elements such as serum proteins and blood proteins that can affect their ability to effectively carry RNAi payloads to target tissues.

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A new study finds that a placental protein linked with preeclampsia can be targeted by RNA silencing, according to the New Scientist.

A settlement is expected in a Duke University lawsuit hinging on using falsified data to win grants, Retraction Watch and Science report.

A phylogenetic analysis finds that the rare hemimastigotes form their own supra-kingdom, CBC reports.

In PNAS this week: approach for analyzing the expression of endogenous retroviruses, circular RNAs that influence host-virus interactions, and more.

Dec
03
Sponsored by
Advanced Cell Diagnostics

This webinar will demonstrate how a research team at the National Institutes of Health evaluated a novel in situ hybridization approach and applied it to study splice variants related to schizophrenia.

Dec
04
Sponsored by
Sophia Genetics

This webinar will discuss the use of clinical-grade exome analysis application in complex case investigations.