In an effort to improve the screening and selection of lipid nanoparticle delivery vehicles for siRNA therapeutics, researchers from Merck have developed an in vitro assay designed to test how the particles will behave in vivo.

After systemic administration, lipid nanoparticles are exposed to a variety of biological elements such as serum proteins and blood proteins that can affect their ability to effectively carry RNAi payloads to target tissues.

Get the full story with
GenomeWeb Premium

Only $95 for the
first 90 days*

A trial upgrade to GenomeWeb Premium gives you full site access, interest-based email alerts, access to archives, and more. Never miss another important industry story.

Try GenomeWeb Premium now.

Already a GenomeWeb Premium member? Login Now.
Or, See if your institution qualifies for premium access.

*Before your trial expires, we’ll put together a custom quote with your long-term premium options.

Not ready for premium?

Browse our free articles
You can still register for access to our free content.

In Science this week: gene linked to expansion of the human neocortex, and more.

The National Institute of General Medical Sciences director says changes the agency made have allow it to boost success rates.

Ancient DNA indicates Stone Age, hunter-gather inhabitants of Britain imported wheat.

Joel Achenbach explores at National Geographic why people find science difficult to believe.