NEW YORK (GenomeWeb) – Despite the specificity offered by RNAi, designing siRNAs capable of silencing specific alleles remains a challenge. As part of an effort to overcome this issue, researchers from Japan's National Institute of Neuroscience have developed two formulas for determining allele-specific siRNAs.

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A fire at a Manchester hospital may have destroyed lab equipment and data, the Guardian reports.

Researchers generate a genetic database from skeletal remains from the 1845 Franklin Expedition to the Arctic, Live Science reports.

Researchers in China have begun another trial using CRISPR/Cas9 approaches in cancer patients, according to the Wall Street Journal.

In Science this week: human DNA found in sediments from archeological sites lacking bones, and more.