NEW YORK (GenomeWeb) – Despite the specificity offered by RNAi, designing siRNAs capable of silencing specific alleles remains a challenge. As part of an effort to overcome this issue, researchers from Japan's National Institute of Neuroscience have developed two formulas for determining allele-specific siRNAs.

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The US Food and Drug Administration has approved Kite Pharmaceuticals' CAR T-cell therapy for large B-cell lymphomas, the New York Times reports.

Kaiser Health News reports that gene therapies could cost more than a million dollars.

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

In Nature this week: variants associated with obsessive-compulsive disorder, review of key CRISPR enzymes, and more.