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It seems that in most cases, big pharma is maintaining a wait-and-see attitude on RNAi-based drugs and will continue to rely on small- molecule approaches to therapeutics. But as patents on blockbuster medicines expire and drug pipelines increasingly run dry, some are looking into whether RNAi can be used for more than target validation. Such is the case with a deal just announced between Sirna Therapeutics and Eli Lilly.

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The Lancet has made changes to its peer-review process in response to its recent retraction of a COVID-19-related paper, Science reports.

The New York Times reports that a series of emails show how Department of Health and Human Services officials sought to silence the Centers for Disease Control and Prevention.

A new initiative aims to move Australia's genome sequencing labs onto one system, the Sydney Morning Herald reports.

In PLOS this week: recessive mutation tied to early-onset dilated cardiomyopathy, epigenetic analysis of lung adenocarcinoma, and more.

Oct
28
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NRGene

Molecular breeding methods such as genomic selection and genome-wide association studies often require high-density genotypic data from many samples, but the cost and complexity of genotyping at this scale may be prohibitive.