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TGen Researchers Link miRNA-328 with Brain Metastasis

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Researchers from the Translational Genomics Research Institute have published a study showing that microRNA-328 can predict lung cancers that could spread to the brain.

In collaboration with investigators from Scottsdale Healthcare, the TGen team reported in the International Journal of Cancer that an examination of tumor specimens linked over-expression of the miRNA with increased cancer cell migration.

“The elevated expression of microRNA-328 in both thoracic and brain NSCLC samples suggests this microRNA may be involved in ‘brain-seeking’ metastatic potential,” Shilpi Arora, a TGen scientist and the paper’s first author, said in a statement.

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