Tekmira Pharmaceuticals this week announced that it has expanded its pipeline with the addition of an siRNA-based drug candidate for alcohol dependence.

The company separately updated its cash guidance, stating that it has enough funds to carry it into the second half of 2013.

The new drug program focuses on aldehyde dehydrogenase 2, or ALDH2, which the company said is a “key enzyme" in ethanol metabolism.

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Rare gene mutations are guiding the search for drugs to manage chronic pain without opioids, according to CNBC.

The new Francis Crick Institute building can get too noisy for some researchers to concentrate, according to the Guardian.

CBS News reports that there are still many vacancies at the White House Office of Science and Technology Policy, but that it's uncertain whether they will be filled.

In Nucleic Acids Research this week: pipeline to analyze and visualize bacterial genomes, database of global set of human genomes, and more.