NEW YORK (GenomeWeb) – Tekmira Pharmaceuticals this week announced that it is beginning a Phase I/II trial of its cancer drug TKM-PLK1 in patients with hepatocellular carcinoma (HCC).

TKM-PLK1 uses the company's proprietary lipid nanoparticles to deliver siRNAs against polo-like kinase 1, a serine/threonine kinase that is key to cell progression and is over-expressed in a number of cancer types.

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