A team of researchers from Stanford University has shown that sustained, high-level shRNA expression in murine livers can result in severe toxicity and death -- possibly as a result of the shRNAs interfering with endogenous microRNA processing machinery.

Although the findings, which appear in this week's Nature, have raised questions over the use of shRNA as a therapeutic modality, Mark Kay, a professor at Stanford's School of Medicine and co-author of the paper, called them "encouraging."

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Direct-to-consumer genetic testing companies have offered to test families separated at the southern US border, but that raises ethical issues.

CNBC reports that confirming a positive result from 23andMe's BRCA health report can be expensive.

The New York Times reports on a project to develop a tree DNA database to uncover illegal logging.

In PLOS this week: links between gut microbiome and colorectal cancer mutations, targeted sequencing uncovers genetic susceptibilities to epilepsy in Koreans, and more.

Jul
19
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Thermo Fisher Scientific

This webinar will discuss how ultra-highly sensitive and customizable targeted next-generation sequencing panels are applied in inherited disease research.