At St. Jude Children’s Research Hospital, John Nitiss is trying to figure out just how certain cancer drugs — those that target topoisomerases — work. In doing so, he is hoping to specifically discover where they interact on the enzyme and what exactly is going on in a cancer cell once the drug begins to act on the enzyme.

While Nitiss previously conducted this drug action research in yeast, he is now turning his attention to mammalian cells with the help of RNA interference.

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A fire at a Manchester hospital may have destroyed lab equipment and data, the Guardian reports.

Researchers generate a genetic database from skeletal remains from the 1845 Franklin Expedition to the Arctic, Live Science reports.

Researchers in China have begun another trial using CRISPR/Cas9 approaches in cancer patients, according to the Wall Street Journal.

In Science this week: human DNA found in sediments from archeological sites lacking bones, and more.