At St. Jude Children’s Research Hospital, John Nitiss is trying to figure out just how certain cancer drugs — those that target topoisomerases — work. In doing so, he is hoping to specifically discover where they interact on the enzyme and what exactly is going on in a cancer cell once the drug begins to act on the enzyme.

While Nitiss previously conducted this drug action research in yeast, he is now turning his attention to mammalian cells with the help of RNA interference.

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A former Synthetic Genomics attorney alleges that the firm discriminated against her and other female employees, according to the San Diego Union-Tribune.

Due to privacy and lab certification questions, the planned giveaway of Orig3n testing kits at a Baltimore Ravens game was suspended.

Alnylam reports positive results from its phase 3 clinical trial of an RNAi-based drug, according to Stat News.

In Cell this week: adult mesenchymal cell populations in mouse lung, genetic diversity in HPV16 and cancer risk protection, and more.