Title: Composition and Method for In Vivo and in Vitro Attenuation of Gene Expression Using Double-Stranded RNA. Number: 20040147475. Filed: Feb. 5, 2004. Lead Inventor: Yin-Xiong Li, Medical College of Georgia Research Institute.
According to the abstract, the invention relates to the “introduction of double-stranded RNA into cells, cell culture, organs and tissue, and whole organisms, particularly vertebrates, [in order to] specifically [attenuate] gene expression.”